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The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters.
Arthur, Robert K; An, Ningfei; Khan, Saira; McNerney, Megan E.
Afiliação
  • Arthur RK; Department of Pathology, Department of Pediatrics, Section of Hematology/Oncology, and The University of Chicago Medicine Comprehensive Cancer Center, The University of Chicago, Chicago, IL 60637, USA.
  • An N; Department of Pathology, Department of Pediatrics, Section of Hematology/Oncology, and The University of Chicago Medicine Comprehensive Cancer Center, The University of Chicago, Chicago, IL 60637, USA.
  • Khan S; Department of Pathology, Department of Pediatrics, Section of Hematology/Oncology, and The University of Chicago Medicine Comprehensive Cancer Center, The University of Chicago, Chicago, IL 60637, USA.
  • McNerney ME; Department of Pathology, Department of Pediatrics, Section of Hematology/Oncology, and The University of Chicago Medicine Comprehensive Cancer Center, The University of Chicago, Chicago, IL 60637, USA.
Nucleic Acids Res ; 45(11): 6350-6361, 2017 Jun 20.
Article em En | MEDLINE | ID: mdl-28369554
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Transcrição Gênica / Proteínas Nucleares / Elementos Facilitadores Genéticos / Regiões Promotoras Genéticas / Proteínas de Homeodomínio Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Transcrição Gênica / Proteínas Nucleares / Elementos Facilitadores Genéticos / Regiões Promotoras Genéticas / Proteínas de Homeodomínio Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2017 Tipo de documento: Article