Antiphospholipid syndrome in a patient with rheumatoid arthritis.
Cutis
; 99(3): E21-E24, 2017 Mar.
Article
em En
| MEDLINE
| ID: mdl-28398429
ABSTRACT
Antiphospholipid syndrome (APS) is an autoimmune condition characterized by a thrombotic event and/or pregnancy morbidity in the presence of persistently elevated antiphospholipid (aPL) antibody titers, which are most prevalent in patients with systemic lupus erythematosus but also have been associated with other autoimmune, malignant, and infectious diseases. In contrast to the clear correlation between high aPL antibody titers and thrombotic events in patients with systemic lupus erythematosus, the pathogenic role of these autoantibodies in association with other diseases, such as rheumatoid arthritis (RA), is not as well defined. We report a case of APS manifesting as cutaneous ulceration and necrosis in a patient with severe RA.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Úlcera Cutânea
/
Síndrome Antifosfolipídica
/
Anticorpos Antifosfolipídeos
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Cutis
Ano de publicação:
2017
Tipo de documento:
Article