Startle responses in functional jerky movement disorders are increased but have a normal pattern.
Parkinsonism Relat Disord
; 40: 27-32, 2017 Jul.
Article
em En
| MEDLINE
| ID: mdl-28410805
ABSTRACT
BACKGROUND:
Exaggerated startle reactions have been frequently described in patients with functional movement disorders (FMD). Long onset latencies and inconsistent recruitment pattern are thought to be a hallmark in these patients. The auditory startle reflex has not been systematically assessed though.OBJECTIVES:
Assessing the frequency and pattern of the early and late component of the auditory startle response in patients with functional jerky movement disorders.METHODS:
A case-control design was used to study 17 patients with functional jerky movement disorders and 15 healthy gender- and age-matched control subjects. The auditory startle reflex was elicited by 108 dB loud tones and assessed with electromyography in multiple muscles.RESULTS:
Response probability of the early and the late response were significantly enlarged in patients with FMD. The early response showed a normal muscle recruitment pattern whereas the late response revealed a more variable pattern compared to controls. The early and late responses showed normal habituation in both groups. Remarkably, a high response rate of the abdominal muscle was noted especially in patients suffering from abdominal jerks.CONCLUSIONS:
This study shows enlarged, but normally patterned early startle responses in FMD. The high response frequency of the late responses found in these patients reflects a behavioral component. Hypersensitivity to external stimuli, often noted in FMD is supported by high response probabilities of both components of the auditory startle response.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reflexo de Sobressalto
/
Estimulação Acústica
/
Transtornos dos Movimentos
Tipo de estudo:
Observational_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Parkinsonism Relat Disord
Ano de publicação:
2017
Tipo de documento:
Article