Genome improvement of the acarbose producer Actinoplanes sp. SE50/110 and annotation refinement based on RNA-seq analysis.

Wolf, Timo; Schneiker-Bekel, Susanne; Neshat, Armin; Ortseifen, Vera; Wibberg, Daniel; Zemke, Till; Pühler, Alfred; Kalinowski, Jörn

Wolf, Timo; Schneiker-Bekel, Susanne; Neshat, Armin; Ortseifen, Vera; Wibberg, Daniel; Zemke, Till; Pühler, Alfred; Kalinowski, Jörn.

Afiliação

Wolf T; Microbial Genomics and Biotechnology, Center for Biotechnology, Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany.
Schneiker-Bekel S; Senior Research Group in Genome Research of Industrial Microorganisms, Center for Biotechnology, Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany.
Neshat A; Microbial Genomics and Biotechnology, Center for Biotechnology, Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany.
Ortseifen V; Senior Research Group in Genome Research of Industrial Microorganisms, Center for Biotechnology, Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany.
Wibberg D; Senior Research Group in Genome Research of Industrial Microorganisms, Center for Biotechnology, Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany.
Zemke T; Product Supply, Bayer Pharma AG, Friedrich Ebert Str. 217-475, 42117 Wuppertal, Germany.
Pühler A; Senior Research Group in Genome Research of Industrial Microorganisms, Center for Biotechnology, Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany.
Kalinowski J; Microbial Genomics and Biotechnology, Center for Biotechnology, Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany. Electronic address: Joern.Kalinowski@Cebitec.Uni-Bielefeld.de.

J Biotechnol ; 251: 112-123, 2017 Jun 10.

Article em En | MEDLINE | ID: mdl-28427920

Assuntos

Genoma Bacteriano; Micromonosporaceae/genética; Acarbose/metabolismo; DNA Complementar/genética; Micromonosporaceae/metabolismo; Anotação de Sequência Molecular; Análise de Sequência de RNA

Palavras-chave

Acarbose; Actinoplanes; Attenuation; Cis-regulatory elements; RNA-seq; Secondary metabolite gene clusters

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genoma Bacteriano / Micromonosporaceae Idioma: En Revista: J Biotechnol Ano de publicação: 2017 Tipo de documento: Article

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