Engineered Regulatory Systems Modulate Gene Expression of Human Commensals in the Gut.

Lim, Bentley; Zimmermann, Michael; Barry, Natasha A; Goodman, Andrew L

Lim, Bentley; Zimmermann, Michael; Barry, Natasha A; Goodman, Andrew L.

Afiliação

Lim B; Department of Microbial Pathogenesis and Microbial Sciences Institute, Yale University School of Medicine, New Haven, CT 06536-0812, USA.
Zimmermann M; Department of Microbial Pathogenesis and Microbial Sciences Institute, Yale University School of Medicine, New Haven, CT 06536-0812, USA.
Barry NA; Department of Microbial Pathogenesis and Microbial Sciences Institute, Yale University School of Medicine, New Haven, CT 06536-0812, USA.
Goodman AL; Department of Microbial Pathogenesis and Microbial Sciences Institute, Yale University School of Medicine, New Haven, CT 06536-0812, USA. Electronic address: andrew.goodman@yale.edu.

Cell ; 169(3): 547-558.e15, 2017 04 20.

Article em En | MEDLINE | ID: mdl-28431252

Assuntos

Bacteroides/genética; Microbioma Gastrointestinal; Engenharia Genética/métodos; Animais; Bacteroides/classificação; Expressão Gênica; Humanos; Camundongos; Neuraminidase/metabolismo; Regiões Promotoras Genéticas

Palavras-chave

Bacteroides; anhydrotetracycline; gene regulation; gut; inducible promoter; microbiome; sialic acid; synthetic biology

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Bacteroides / Engenharia Genética / Microbioma Gastrointestinal Limite: Animals / Humans Idioma: En Revista: Cell Ano de publicação: 2017 Tipo de documento: Article

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