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Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease.
Coffey, Sydney R; Bragg, Robert M; Minnig, Shawn; Ament, Seth A; Cantle, Jeffrey P; Glickenhaus, Anne; Shelnut, Daniel; Carrillo, José M; Shuttleworth, Dominic D; Rodier, Julie-Anne; Noguchi, Kimihiro; Bennett, C Frank; Price, Nathan D; Kordasiewicz, Holly B; Carroll, Jeffrey B.
Afiliação
  • Coffey SR; Behavioral Neuroscience Program, Psychology Department, Western Washington University, Bellingham, WA, United States of America.
  • Bragg RM; Behavioral Neuroscience Program, Psychology Department, Western Washington University, Bellingham, WA, United States of America.
  • Minnig S; Behavioral Neuroscience Program, Psychology Department, Western Washington University, Bellingham, WA, United States of America.
  • Ament SA; Institute for Genome Sciences and Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, United States of America.
  • Cantle JP; Institute for Systems Biology, Seattle, WA, United States of America.
  • Glickenhaus A; Behavioral Neuroscience Program, Psychology Department, Western Washington University, Bellingham, WA, United States of America.
  • Shelnut D; Behavioral Neuroscience Program, Psychology Department, Western Washington University, Bellingham, WA, United States of America.
  • Carrillo JM; Department of Mathematics, Western Washington University, Bellingham, WA, United States of America.
  • Shuttleworth DD; Behavioral Neuroscience Program, Psychology Department, Western Washington University, Bellingham, WA, United States of America.
  • Rodier JA; Behavioral Neuroscience Program, Psychology Department, Western Washington University, Bellingham, WA, United States of America.
  • Noguchi K; INSERM U1216, Grenoble Institute of Neuroscience, Grenoble, France. Université Grenoble Alpes, Grenoble, France.
  • Bennett CF; Department of Mathematics, Western Washington University, Bellingham, WA, United States of America.
  • Price ND; Ionis Pharmaceuticals, Carlsbad, CA, United States of America.
  • Kordasiewicz HB; Institute for Genome Sciences and Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, United States of America.
  • Carroll JB; Ionis Pharmaceuticals, Carlsbad, CA, United States of America.
PLoS One ; 12(4): e0175968, 2017.
Article em En | MEDLINE | ID: mdl-28453524
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Doença de Huntington / Inativação Gênica / Proteína Huntingtina Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: PLoS One Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Doença de Huntington / Inativação Gênica / Proteína Huntingtina Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: PLoS One Ano de publicação: 2017 Tipo de documento: Article