Real-Time Imaging of the Azole Class of Antifungal Drugs in Live Candida Cells.

Benhamou, Raphael I; Bibi, Maayan; Steinbuch, Kfir B; Engel, Hamutal; Levin, Maayan; Roichman, Yael; Berman, Judith; Fridman, Micha

Benhamou, Raphael I; Bibi, Maayan; Steinbuch, Kfir B; Engel, Hamutal; Levin, Maayan; Roichman, Yael; Berman, Judith; Fridman, Micha.

Afiliação

Benhamou RI; School of Chemistry, Raymond & Beverly Sackler Faculty of Exact Sciences, Tel Aviv University , Tel Aviv, 6997801, Israel.
Bibi M; Dept. of Molecular Microbiology & Biotechnology, School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University , Tel Aviv, 6997801, Israel.
Steinbuch KB; School of Chemistry, Raymond & Beverly Sackler Faculty of Exact Sciences, Tel Aviv University , Tel Aviv, 6997801, Israel.
Engel H; Blavatnik Center for Drug Discovery, Tel Aviv University , Tel Aviv, 6997801, Israel.
Levin M; School of Chemistry, Raymond & Beverly Sackler Faculty of Exact Sciences, Tel Aviv University , Tel Aviv, 6997801, Israel.
Roichman Y; School of Chemistry, Raymond & Beverly Sackler Faculty of Exact Sciences, Tel Aviv University , Tel Aviv, 6997801, Israel.
Berman J; Dept. of Molecular Microbiology & Biotechnology, School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University , Tel Aviv, 6997801, Israel.
Fridman M; School of Chemistry, Raymond & Beverly Sackler Faculty of Exact Sciences, Tel Aviv University , Tel Aviv, 6997801, Israel.

ACS Chem Biol ; 12(7): 1769-1777, 2017 07 21.

Article em En | MEDLINE | ID: mdl-28472585

Assuntos

Antifúngicos/química; Azóis/metabolismo; Candida/química; Corantes Fluorescentes/metabolismo; Animais; Azóis/química; Candida/enzimologia; Domínio Catalítico; Células Cultivadas; Sistema Enzimático do Citocromo P-450/química; Sistema Enzimático do Citocromo P-450/genética; Sistema Enzimático do Citocromo P-450/metabolismo; Corantes Fluorescentes/síntese química; Microscopia de Fluorescência; Simulação de Acoplamento Molecular; Mutação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azóis / Candida / Corantes Fluorescentes / Antifúngicos Limite: Animals Idioma: En Revista: ACS Chem Biol Ano de publicação: 2017 Tipo de documento: Article

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