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Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells.
Chen, Haibo; Luo, Dingyuan; Zhang, Lin; Lin, Xiaofeng; Luo, Qiuyun; Yi, Hanjie; Wang, Jing; Yan, Xianglei; Li, Baoxia; Chen, Yuelei; Liu, Xingguang; Zhang, Hong; Liu, Sheng; Qiu, Miaozhen; Yang, Dajun; Jiang, Ningyi.
Afiliação
  • Chen H; Department of Nuclear Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
  • Luo D; Department of Vascular and Thyroid Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
  • Zhang L; Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China.
  • Lin X; Department of Clinical Laboratory, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China.
  • Luo Q; Department of Nuclear Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
  • Yi H; Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China.
  • Wang J; Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China.
  • Yan X; Department of Pharmacy, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
  • Li B; Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China.
  • Chen Y; Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China.
  • Liu X; The State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Zhang H; Department of Nuclear Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
  • Liu S; Department of Nuclear Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
  • Qiu M; Department of Nuclear Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
  • Yang D; Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou 510120, China.
  • Jiang N; Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China.
Oncotarget ; 8(26): 43008-43022, 2017 Jun 27.
Article em En | MEDLINE | ID: mdl-28498808
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Compostos de Espiro / Neoplasias da Glândula Tireoide / Carcinoma Papilar / Proteína Supressora de Tumor p53 / Proteínas Proto-Oncogênicas c-mdm2 / Indóis Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Compostos de Espiro / Neoplasias da Glândula Tireoide / Carcinoma Papilar / Proteína Supressora de Tumor p53 / Proteínas Proto-Oncogênicas c-mdm2 / Indóis Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2017 Tipo de documento: Article