Pediatric Gynecologic Cancers.
Curr Oncol Rep
; 19(7): 44, 2017 Jul.
Article
em En
| MEDLINE
| ID: mdl-28501984
ABSTRACT
PURPOSE OF REVIEW Three primary categories of gynecologic cancer are found in pediatric and adolescent patients stromal carcinomas including juvenile granulosa cell tumors and Sertoli-Leydig cell tumors, rhabdomyosarcomas arising from the vagina and cervix (sarcoma botryoides), and ovarian germ cell tumors which comprise a wide range of histologies. These entities are rare and treatment approaches have focused on decreasing late effects of chemotherapy treatment. Here, we review presentation, histologic classifications, diagnosis, and treatment recommendations for pediatric gynecologic cancers. RECENT FINDINGS:
Event-free and overall survival for these cancers is high, and the goals of treatment are minimization of morbidity and preservation of fertility with unilateral salpingo-oophorectomies and limited staging. Surveillance of tumor markers after surgery is helpful in monitoring for disease progression and adjuvant chemotherapy is often reserved for patients at recurrence. Recent literature supports avoiding chemotherapy even in high-grade germ cell tumors in the pediatric population.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Rabdomiossarcoma
/
Tumor de Células de Sertoli-Leydig
/
Neoplasias dos Genitais Femininos
/
Tumor de Células da Granulosa
Tipo de estudo:
Guideline
Limite:
Adolescent
/
Child
/
Female
/
Humans
Idioma:
En
Revista:
Curr Oncol Rep
Ano de publicação:
2017
Tipo de documento:
Article