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Identification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related Hydroxylases.
Petrassi, Mike; Barber, Rob; Be, Celine; Beach, Sarah; Cox, Brian; D'Souza, Anne-Marie; Duggan, Nick; Hussey, Martin; Fox, Roy; Hunt, Peter; Jarai, Gabor; Kosaka, Takatoshi; Oakley, Paul; Patel, Viral; Press, Neil; Rowlands, David; Scheufler, Clemens; Schmidt, Oliver; Srinivas, Honnappa; Turner, Mary; Turner, Rob; Westwick, John; Wolfreys, Alison; Pathan, Nuzhat; Watson, Simon; Thomas, Matthew.
Afiliação
  • Petrassi M; Genomics Institute of the Novartis Research Foundation, San DiegoCA, USA.
  • Barber R; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Be C; Novartis Institutes for BioMedical ResearchBasel, Switzerland.
  • Beach S; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Cox B; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • D'Souza AM; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Duggan N; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Hussey M; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Fox R; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Hunt P; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Jarai G; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Kosaka T; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Oakley P; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Patel V; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Press N; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Rowlands D; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Scheufler C; Novartis Institutes for BioMedical ResearchBasel, Switzerland.
  • Schmidt O; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Srinivas H; Novartis Institutes for BioMedical ResearchBasel, Switzerland.
  • Turner M; Genomics Institute of the Novartis Research Foundation, San DiegoCA, USA.
  • Turner R; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Westwick J; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Wolfreys A; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Pathan N; Genomics Institute of the Novartis Research Foundation, San DiegoCA, USA.
  • Watson S; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
  • Thomas M; Respiratory Disease Area, Novartis Institutes for BioMedical ResearchHorsham, UK.
Front Pharmacol ; 8: 240, 2017.
Article em En | MEDLINE | ID: mdl-28529483
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Front Pharmacol Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Front Pharmacol Ano de publicação: 2017 Tipo de documento: Article