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Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug.
Wu, Hao; Esteve, Eduardo; Tremaroli, Valentina; Khan, Muhammad Tanweer; Caesar, Robert; Mannerås-Holm, Louise; Ståhlman, Marcus; Olsson, Lisa M; Serino, Matteo; Planas-Fèlix, Mercè; Xifra, Gemma; Mercader, Josep M; Torrents, David; Burcelin, Rémy; Ricart, Wifredo; Perkins, Rosie; Fernàndez-Real, José Manuel; Bäckhed, Fredrik.
Afiliação
  • Wu H; Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
  • Esteve E; Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona, Hospital Josep Trueta, Girona, Spain.
  • Tremaroli V; Departament de Medicina, Facultat de Medicina, University of Girona, Girona, Spain.
  • Khan MT; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.
  • Caesar R; Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
  • Mannerås-Holm L; Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
  • Ståhlman M; Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
  • Olsson LM; Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
  • Serino M; Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
  • Planas-Fèlix M; Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
  • Xifra G; IRSD, Université de Toulouse, INSERM, INRA, ENVT, UPS, Toulouse, France.
  • Mercader JM; Barcelona Supercomputing Center (BSC), Joint BSC-CRG-IRB Research Program in Computational Biology, Barcelona, Spain.
  • Torrents D; Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona, Hospital Josep Trueta, Girona, Spain.
  • Burcelin R; Departament de Medicina, Facultat de Medicina, University of Girona, Girona, Spain.
  • Ricart W; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.
  • Perkins R; Barcelona Supercomputing Center (BSC), Joint BSC-CRG-IRB Research Program in Computational Biology, Barcelona, Spain.
  • Fernàndez-Real JM; Barcelona Supercomputing Center (BSC), Joint BSC-CRG-IRB Research Program in Computational Biology, Barcelona, Spain.
  • Bäckhed F; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.
Nat Med ; 23(7): 850-858, 2017 Jul.
Article em En | MEDLINE | ID: mdl-28530702
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: DNA Bacteriano / Diabetes Mellitus Tipo 2 / Microbioma Gastrointestinal / Hipoglicemiantes / Metformina Tipo de estudo: Clinical_trials Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Med Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: DNA Bacteriano / Diabetes Mellitus Tipo 2 / Microbioma Gastrointestinal / Hipoglicemiantes / Metformina Tipo de estudo: Clinical_trials Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Med Ano de publicação: 2017 Tipo de documento: Article