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GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production.
Miller, Corin; Pachanski, Michele J; Kirkland, Melissa E; Kosinski, Daniel T; Mane, Joel; Bunzel, Michelle; Cao, Jin; Souza, Sarah; Thomas-Fowlkes, Brande; Di Salvo, Jerry; Weinglass, Adam B; Li, Xiaoyan; Myers, Robert W; Knagge, Kevin; Carrington, Paul E; Hagmann, William K; Trujillo, Maria E.
Afiliação
  • Miller C; Departments of Translational Imaging Biomarkers, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Pachanski MJ; In Vivo Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Kirkland ME; In Vivo Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Kosinski DT; In Vivo Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Mane J; In Vivo Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Bunzel M; Departments of Translational Imaging Biomarkers, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Cao J; Departments of Translational Imaging Biomarkers, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Souza S; In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Thomas-Fowlkes B; In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Di Salvo J; In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Weinglass AB; In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Li X; Cardio-Metabolic Diseases, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Myers RW; In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Knagge K; David H Murdock Research Institute, Kannapolis, North Carolina, United States of America.
  • Carrington PE; Cardio-Metabolic Diseases, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Hagmann WK; Chemistry, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Trujillo ME; In Vivo Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
PLoS One ; 12(5): e0176182, 2017.
Article em En | MEDLINE | ID: mdl-28542610
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzopiranos / Glicemia / Tiazolidinedionas / Receptores Acoplados a Proteínas G / Diabetes Mellitus Experimental / Glucose / Hipoglicemiantes Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzopiranos / Glicemia / Tiazolidinedionas / Receptores Acoplados a Proteínas G / Diabetes Mellitus Experimental / Glucose / Hipoglicemiantes Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Ano de publicação: 2017 Tipo de documento: Article