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IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression.
Wang, Chenhui; Zhang, Cun-Jin; Martin, Bradley N; Bulek, Katarzyna; Kang, Zizhen; Zhao, Junjie; Bian, Guanglin; Carman, Julie A; Gao, Ji; Dongre, Ashok; Xue, Haibo; Miller, Stephen D; Qian, Youcun; Hambardzumyan, Dolores; Hamilton, Tom; Ransohoff, Richard M; Li, Xiaoxia.
Afiliação
  • Wang C; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
  • Zhang CJ; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Martin BN; Wuhan Institute of Biotechnology, Wuhan 430075, China.
  • Bulek K; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Kang Z; Department of Neurology and Immunology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.
  • Zhao J; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Bian G; Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106, USA.
  • Carman JA; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Gao J; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Dongre A; Shanghai Institute of Immunology, Shanghai Jiaotong University of School of Medicine, 280 South Chongqing Rd, Huangpu, Shanghai 200025, China.
  • Xue H; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Miller SD; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Qian Y; Discovery Biology, Bristol-Myers Squibb, Princeton, New Jersey 08540, USA.
  • Hambardzumyan D; Discovery Biology, Bristol-Myers Squibb, Princeton, New Jersey 08540, USA.
  • Hamilton T; Discovery Biology, Bristol-Myers Squibb, Princeton, New Jersey 08540, USA.
  • Ransohoff RM; The Department of Endocrinology and Metabolism, Binzhou Medical University Hospital. Binzhou City, Shandong Province 256603, China.
  • Li X; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Nat Commun ; 8: 15508, 2017 05 31.
Article em En | MEDLINE | ID: mdl-28561022
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-17 / Encefalomielite Autoimune Experimental / Receptor Notch1 / Células Th17 / Células Precursoras de Oligodendrócitos / Esclerose Múltipla Limite: Animals / Female / Humans Idioma: En Revista: Nat Commun Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-17 / Encefalomielite Autoimune Experimental / Receptor Notch1 / Células Th17 / Células Precursoras de Oligodendrócitos / Esclerose Múltipla Limite: Animals / Female / Humans Idioma: En Revista: Nat Commun Ano de publicação: 2017 Tipo de documento: Article