MCL Plays an Anti-Inflammatory Role in <i>Mycobacterium tuberculosis</i>-Induced Immune Response by Inhibiting NF-<i>&#954;</i>B and NLRP3 Inflammasome Activation.

Zhang, Qingwen; Jiang, Xinru; He, Weigang; Wei, Kailin; Sun, Jinxia; Qin, Xiangyang; Zheng, Yuejuan; Jiang, Xin

MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation.

Zhang, Qingwen; Jiang, Xinru; He, Weigang; Wei, Kailin; Sun, Jinxia; Qin, Xiangyang; Zheng, Yuejuan; Jiang, Xin.

Afiliação

Zhang Q; Department of Immunology and Microbiology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Jiang X; Department of Immunology and Microbiology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
He W; Department of Immunology and Microbiology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Wei K; Major in Biology, The University of British Columbia, Vancouver, Canada V6T 1Z4.
Sun J; Department of Immunology and Microbiology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Qin X; Department of Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an, Shaanxi 710034, China.
Zheng Y; Department of Immunology and Microbiology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Jiang X; Department of Immunology and Microbiology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.

Mediators Inflamm ; 2017: 2432904, 2017.

Article em En | MEDLINE | ID: mdl-28642632

Assuntos

Anti-Inflamatórios/uso terapêutico; Inflamassomos/efeitos dos fármacos; Inflamassomos/metabolismo; Mycobacterium tuberculosis/imunologia; NF-kappa B/metabolismo; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Sesquiterpenos de Guaiano/uso terapêutico; Animais; Interleucina-1beta/metabolismo; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Camundongos; Fosforilação/efeitos dos fármacos; Células RAW 264.7; Transdução de Sinais/efeitos dos fármacos; Fator de Necrose Tumoral alfa/metabolismo

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 Base de dados: MEDLINE Assunto principal: NF-kappa B / Sesquiterpenos de Guaiano / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Anti-Inflamatórios / Mycobacterium tuberculosis Limite: Animals Idioma: En Revista: Mediators Inflamm Ano de publicação: 2017 Tipo de documento: Article

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