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Sam68 Allows Selective Targeting of Human Cancer Stem Cells.
Benoit, Yannick D; Mitchell, Ryan R; Risueño, Ruth M; Orlando, Luca; Tanasijevic, Borko; Boyd, Allison L; Aslostovar, Lili; Salci, Kyle R; Shapovalova, Zoya; Russell, Jennifer; Eguchi, Masakatsu; Golubeva, Diana; Graham, Monica; Xenocostas, Anargyros; Trus, Michael R; Foley, Ronan; Leber, Brian; Collins, Tony J; Bhatia, Mickie.
Afiliação
  • Benoit YD; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada.
  • Mitchell RR; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada.
  • Risueño RM; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada.
  • Orlando L; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada.
  • Tanasijevic B; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada.
  • Boyd AL; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada.
  • Aslostovar L; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, ON
  • Salci KR; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada.
  • Shapovalova Z; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada.
  • Russell J; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada.
  • Eguchi M; Theriac Pharmaceutical Corporation Research Institute, 600 Broadway Suite 580 Fl 5, Seattle, WA 98122, USA.
  • Golubeva D; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada.
  • Graham M; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada.
  • Xenocostas A; Department of Medicine, Division of Hematology, Schulich School of Medicine, University of Western Ontario, London, ON N6A 3K7, Canada.
  • Trus MR; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Foley R; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Leber B; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Collins TJ; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada.
  • Bhatia M; McMaster Stem Cell and Cancer Research Institute, Faculty of Health Sciences, McMaster University, 1280 Main Street West, MDCL 5029, Hamilton, ON L8S 4L8, Canada; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, ON
Cell Chem Biol ; 24(7): 833-844.e9, 2017 Jul 20.
Article em En | MEDLINE | ID: mdl-28648376
Assuntos
Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Proteínas de Ligação a DNA/metabolismo; Células-Tronco Neoplásicas/metabolismo; Fragmentos de Peptídeos/metabolismo; Proteínas de Ligação a RNA/metabolismo; Sialoglicoproteínas/metabolismo; Proteínas Adaptadoras de Transdução de Sinal/antagonistas & inibidores; Proteínas Adaptadoras de Transdução de Sinal/genética; Adulto; Idoso; Animais; Apoptose/efeitos dos fármacos; Compostos Azabicíclicos/farmacologia; Neoplasias da Mama/metabolismo; Neoplasias da Mama/patologia; Compostos Bicíclicos Heterocíclicos com Pontes/farmacologia; Diferenciação Celular/efeitos dos fármacos; Células Cultivadas; Neoplasias do Colo/metabolismo; Neoplasias do Colo/patologia; Proteínas de Ligação a DNA/antagonistas & inibidores; Proteínas de Ligação a DNA/genética; Feminino; Humanos; Leucemia Mieloide Aguda/metabolismo; Leucemia Mieloide Aguda/patologia; Masculino; Camundongos; Camundongos Endogâmicos NOD; Pessoa de Meia-Idade; Células-Tronco Neoplásicas/citologia; Células-Tronco Neoplásicas/transplante; Organofosfatos/farmacologia; Fragmentos de Peptídeos/antagonistas & inibidores; Fragmentos de Peptídeos/genética; Proteínas Proto-Oncogênicas c-myc/metabolismo; Pirimidinonas/farmacologia; Interferência de RNA; Proteínas de Ligação a RNA/antagonistas & inibidores; Proteínas de Ligação a RNA/genética; Sialoglicoproteínas/antagonistas & inibidores; Sialoglicoproteínas/genética; Sumoilação/efeitos dos fármacos; Transcriptoma/efeitos dos fármacos; Via de Sinalização Wnt/efeitos dos fármacos; beta Catenina/metabolismo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Sialoglicoproteínas / Células-Tronco Neoplásicas / Proteínas de Ligação a RNA / Proteínas Adaptadoras de Transdução de Sinal / Proteínas de Ligação a DNA Idioma: En Revista: Cell Chem Biol Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Sialoglicoproteínas / Células-Tronco Neoplásicas / Proteínas de Ligação a RNA / Proteínas Adaptadoras de Transdução de Sinal / Proteínas de Ligação a DNA Idioma: En Revista: Cell Chem Biol Ano de publicação: 2017 Tipo de documento: Article