Prodrugs in medicinal chemistry and enzyme prodrug therapies.

Walther, Raoul; Rautio, Jarkko; Zelikin, Alexander N

Walther, Raoul; Rautio, Jarkko; Zelikin, Alexander N.

Afiliação

Walther R; Department of Chemistry, Aarhus University, Denmark.
Rautio J; School of Pharmacy, University of Eastern Finland, Kuopio, Finland. Electronic address: jarkko.rautio@uef.fi.
Zelikin AN; Department of Chemistry, Aarhus University, Denmark; iNano Interdisciplinary Nanoscience Centre, Aarhus University, Denmark. Electronic address: zelikin@chem.au.dk.

Adv Drug Deliv Rev ; 118: 65-77, 2017 09 01.

Article em En | MEDLINE | ID: mdl-28676386

Assuntos

Pró-Fármacos/metabolismo; Pró-Fármacos/uso terapêutico; Animais; Química Farmacêutica/métodos; Desenho de Fármacos; Terapia Enzimática/métodos; Humanos

Palavras-chave

Drug delivery; Enzyme; Enzyme prodrug therapy; Prodrugs; Self immolative linkers

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos Limite: Animals / Humans Idioma: En Revista: Adv Drug Deliv Rev Ano de publicação: 2017 Tipo de documento: Article

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