Lipolytic effect of compounds isolated from leaves of mulberry (Morus alba L.) in 3T3-L1 adipocytes.
Nat Prod Res
; 32(16): 1963-1966, 2018 Aug.
Article
em En
| MEDLINE
| ID: mdl-28722505
ABSTRACT
In this study, 19 known compounds were isolated from mulberry (Morus alba L.) leaves. The lipid accumulation inhibitory activity of the isolated compounds was investigated. Compounds 4 and 12 showed good anti-adipogenic activity based on 3T3-L1 adipocytes with values of 36.6 ± 9.0 and 34.7 ± 4.0%, respectively. In addition, compounds 3, 6 and 15 showed significant inhibitory activity with values from 15.4 to 21.2% and compounds 2, 8-9 and 17-18 exhibited weak activity with values ranging from 2.1 to 10.7% at a concentration of 40.0 µM. These results show the potentiality that mulberry leaf is an excellent inhibitory phytochemical source against lipid accumulation.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Extratos Vegetais
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Adipócitos
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Morus
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Lipólise
Limite:
Animals
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2018
Tipo de documento:
Article