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Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and -C2.
Ma, Meisheng; Liu, Jun-Jie; Li, Yan; Huang, Yuwei; Ta, Na; Chen, Yang; Fu, Hua; Ye, Ming-Da; Ding, Yuehe; Huang, Weijiao; Wang, Jia; Dong, Meng-Qiu; Yu, Li; Wang, Hong-Wei.
Afiliação
  • Ma M; The State Key Laboratory of Membrane Biology, Tsinghua University-Peking University Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Liu JJ; Ministry of Education Key Laboratory of Protein Sciences, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Li Y; Joint Graduate Program of Peking-Tsinghua-National Institute of Biological Science, Tsinghua University, Beijing 100084, China.
  • Huang Y; Current address: Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  • Ta N; Ministry of Education Key Laboratory of Protein Sciences, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Chen Y; The State Key Laboratory of Membrane Biology, Tsinghua University-Peking University Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Fu H; Joint Graduate Program of Peking-Tsinghua-National Institute of Biological Science, Tsinghua University, Beijing 100084, China.
  • Ye MD; The State Key Laboratory of Membrane Biology, Tsinghua University-Peking University Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Ding Y; The State Key Laboratory of Membrane Biology, Tsinghua University-Peking University Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Huang W; MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100730, China.
  • Wang J; Ministry of Education Key Laboratory of Protein Sciences, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Dong MQ; National Institute of Biological Sciences, Beijing 102206, China.
  • Yu L; Ministry of Education Key Laboratory of Protein Sciences, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Wang HW; Ministry of Education Key Laboratory of Protein Sciences, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Cell Res ; 27(8): 989-1001, 2017 Aug.
Article em En | MEDLINE | ID: mdl-28731030
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Classe II de Fosfatidilinositol 3-Quinases / Complexos Multienzimáticos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Res Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Classe II de Fosfatidilinositol 3-Quinases / Complexos Multienzimáticos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Res Ano de publicação: 2017 Tipo de documento: Article