RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse.

Fernandez-Cortes, Fernando; Serafim, Tiago D; Wilkes, Jonathan M; Jones, Nathaniel G; Ritchie, Ryan; McCulloch, Richard; Mottram, Jeremy C

Fernandez-Cortes, Fernando; Serafim, Tiago D; Wilkes, Jonathan M; Jones, Nathaniel G; Ritchie, Ryan; McCulloch, Richard; Mottram, Jeremy C.

Afiliação

Fernandez-Cortes F; Wellcome Centre for Molecular Parasitology and Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Serafim TD; Wellcome Centre for Molecular Parasitology and Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Wilkes JM; Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.
Jones NG; Wellcome Centre for Molecular Parasitology and Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Ritchie R; Wellcome Centre for Molecular Parasitology and Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
McCulloch R; Centre for Immunology and Infection, Department of Biology, University of York, Wentworth Way, Heslington, York, UK.
Mottram JC; Wellcome Centre for Molecular Parasitology and Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

Sci Rep ; 7(1): 6156, 2017 07 21.

Article em En | MEDLINE | ID: mdl-28733613

Assuntos

Proteínas Quinases/genética; Análise de Sequência de RNA/métodos; Trypanosoma brucei brucei/patogenicidade; Tripanossomíase Africana/parasitologia; Animais; Genes Essenciais; Camundongos; Proteínas de Protozoários/genética; Interferência de RNA; Transdução de Sinais; Trypanosoma brucei brucei/genética; Tripanossomíase Africana/genética; Tripanossomíase Africana/veterinária; Fatores de Virulência/genética

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Trypanosoma brucei brucei / Tripanossomíase Africana / Análise de Sequência de RNA Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article

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