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Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo.
Lehmann, Mareike; Korfei, Martina; Mutze, Kathrin; Klee, Stephan; Skronska-Wasek, Wioletta; Alsafadi, Hani N; Ota, Chiharu; Costa, Rita; Schiller, Herbert B; Lindner, Michael; Wagner, Darcy E; Günther, Andreas; Königshoff, Melanie.
Afiliação
  • Lehmann M; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München and University Hospital of the Ludwig Maximilians Universität, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Korfei M; Dept of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC), Justus-Liebig-Universität Giessen, Member of the German Center for Lung Research (DZL), Giessen, Germany.
  • Mutze K; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München and University Hospital of the Ludwig Maximilians Universität, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Klee S; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München and University Hospital of the Ludwig Maximilians Universität, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Skronska-Wasek W; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München and University Hospital of the Ludwig Maximilians Universität, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Alsafadi HN; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München and University Hospital of the Ludwig Maximilians Universität, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Ota C; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München and University Hospital of the Ludwig Maximilians Universität, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Costa R; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München and University Hospital of the Ludwig Maximilians Universität, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Schiller HB; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München and University Hospital of the Ludwig Maximilians Universität, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Lindner M; Center for Thoracic Surgery, Asklepios Biobank for Lung Diseases, Comprehensive Pneumology Center, Asklepios Clinic Munich-Gauting, Munich, Germany.
  • Wagner DE; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München and University Hospital of the Ludwig Maximilians Universität, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Günther A; Dept of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC), Justus-Liebig-Universität Giessen, Member of the German Center for Lung Research (DZL), Giessen, Germany.
  • Königshoff M; Agaplesion Lung Clinic Waldhof Elgershausen, Greifenstein, Germany.
Eur Respir J ; 50(2)2017 08.
Article em En | MEDLINE | ID: mdl-28775044
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores / Senescência Celular / Fibrose Pulmonar Idiopática / Células Epiteliais Alveolares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Eur Respir J Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores / Senescência Celular / Fibrose Pulmonar Idiopática / Células Epiteliais Alveolares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Eur Respir J Ano de publicação: 2017 Tipo de documento: Article