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Pseudomonas aeruginosa LasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator-IL-6-antimicrobial-repair pathway.
Saint-Criq, Vinciane; Villeret, Bérengère; Bastaert, Fabien; Kheir, Saadé; Hatton, Aurélie; Cazes, Aurélie; Xing, Zhou; Sermet-Gaudelus, Isabelle; Garcia-Verdugo, Ignacio; Edelman, Aleksander; Sallenave, Jean-Michel.
Afiliação
  • Saint-Criq V; INSERM U1152, Laboratoire d'Excellence Inflamex, Département Hospitalo-Universtaire FIRE (Fibrosis, Inflammation and Remodeling), Université Paris Diderot, Sorbonne Paris Cité, Hopital Bichat - Claude-Bernard, Paris, France.
  • Villeret B; INSERM U1152, Laboratoire d'Excellence Inflamex, Département Hospitalo-Universtaire FIRE (Fibrosis, Inflammation and Remodeling), Université Paris Diderot, Sorbonne Paris Cité, Hopital Bichat - Claude-Bernard, Paris, France.
  • Bastaert F; INSERM U1152, Laboratoire d'Excellence Inflamex, Département Hospitalo-Universtaire FIRE (Fibrosis, Inflammation and Remodeling), Université Paris Diderot, Sorbonne Paris Cité, Hopital Bichat - Claude-Bernard, Paris, France.
  • Kheir S; INSERM U1152, Laboratoire d'Excellence Inflamex, Département Hospitalo-Universtaire FIRE (Fibrosis, Inflammation and Remodeling), Université Paris Diderot, Sorbonne Paris Cité, Hopital Bichat - Claude-Bernard, Paris, France.
  • Hatton A; INSERM U1151, Faculté de Médecine, site Necker, Université Paris Descartes, Paris, France.
  • Cazes A; INSERM U1152, Laboratoire d'Excellence Inflamex, Département Hospitalo-Universtaire FIRE (Fibrosis, Inflammation and Remodeling), Université Paris Diderot, Sorbonne Paris Cité, Hopital Bichat - Claude-Bernard, Paris, France.
  • Xing Z; McMaster Immunology Research Centre, McMaster University, Hamilton, Canada.
  • Sermet-Gaudelus I; INSERM U1151, Faculté de Médecine, site Necker, Université Paris Descartes, Paris, France.
  • Garcia-Verdugo I; INSERM U1152, Laboratoire d'Excellence Inflamex, Département Hospitalo-Universtaire FIRE (Fibrosis, Inflammation and Remodeling), Université Paris Diderot, Sorbonne Paris Cité, Hopital Bichat - Claude-Bernard, Paris, France.
  • Edelman A; INSERM U1151, Faculté de Médecine, site Necker, Université Paris Descartes, Paris, France.
  • Sallenave JM; INSERM U1152, Laboratoire d'Excellence Inflamex, Département Hospitalo-Universtaire FIRE (Fibrosis, Inflammation and Remodeling), Université Paris Diderot, Sorbonne Paris Cité, Hopital Bichat - Claude-Bernard, Paris, France.
Thorax ; 73(1): 49-61, 2018 01.
Article em En | MEDLINE | ID: mdl-28790180
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Metaloendopeptidases / Interleucina-6 / Regulador de Condutância Transmembrana em Fibrose Cística / Fibrose Cística / Células Epiteliais / Imunidade Inata Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Thorax Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Metaloendopeptidases / Interleucina-6 / Regulador de Condutância Transmembrana em Fibrose Cística / Fibrose Cística / Células Epiteliais / Imunidade Inata Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Thorax Ano de publicação: 2018 Tipo de documento: Article