Epidemiology and antifungal susceptibilities of yeast isolates causing invasive infections across urban Beijing, China.
Future Microbiol
; 12: 1075-1086, 2017 09.
Article
em En
| MEDLINE
| ID: mdl-28836465
ABSTRACT
AIM:
To investigate the species distribution and antifungal susceptibility profiles of yeast isolates causing invasive infections across Beijing. MATERIALS &METHODS:
A total of 1201 yeast isolates recovered from blood and other sterile body fluids were correctly identified by matrix-assisted laser desorption/ionization TOF MS supplemented by DNA sequencing. Antifungal susceptibility testing was performed according to the Clinical and Laboratory Standards Institute broth microdilution method.RESULTS:
Candida (95.5%) remained the most common yeast species isolated; Candida albicans (38.8%) and Candida parapsilosis (22.6%) were the leading species of candidemia. Azole resistances were mainly observed in Candida glabrata and Candida tropicalis isolates.CONCLUSION:
This study outlined the epidemiologic data of invasive yeast infections and highlighted the need for continuous monitoring of azole resistances among C. glabrata and C. tropicalis isolates in Beijing.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leveduras
/
Testes de Sensibilidade Microbiana
/
Candidíase Invasiva
Tipo de estudo:
Guideline
/
Screening_studies
País/Região como assunto:
Asia
Idioma:
En
Revista:
Future Microbiol
Ano de publicação:
2017
Tipo de documento:
Article