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A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors.
Brænne, Ingrid; Willenborg, Christina; Tragante, Vinicius; Kessler, Thorsten; Zeng, Lingyao; Reiz, Benedikt; Kleinecke, Mariana; von Ameln, Simon; Willer, Cristen J; Laakso, Markku; Wild, Philipp S; Zeller, Tanja; Wallentin, Lars; Franks, Paul W; Salomaa, Veikko; Dehghan, Abbas; Meitinger, Thomas; Samani, Nilesh J; Asselbergs, Folkert W; Erdmann, Jeanette; Schunkert, Heribert.
Afiliação
  • Brænne I; Institute for Cardiogenetics, University of Lübeck, 23562, Lübeck, Germany.
  • Willenborg C; DZHK (German Research Center for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562, Lübeck, Germany.
  • Tragante V; University Heart Center Lübeck, 23562, Lübeck, Germany.
  • Kessler T; Institute for Cardiogenetics, University of Lübeck, 23562, Lübeck, Germany.
  • Zeng L; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, 3584, Utrecht, The Netherlands.
  • Reiz B; Deutsches Herzzentrum München, Technische Universität München, 80636, München, Germany.
  • Kleinecke M; Deutsches Herzzentrum München, Technische Universität München, 80636, München, Germany.
  • von Ameln S; Institute for Cardiogenetics, University of Lübeck, 23562, Lübeck, Germany.
  • Willer CJ; DZHK (German Research Center for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562, Lübeck, Germany.
  • Laakso M; University Heart Center Lübeck, 23562, Lübeck, Germany.
  • Wild PS; Institute for Cardiogenetics, University of Lübeck, 23562, Lübeck, Germany.
  • Zeller T; DZHK (German Research Center for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562, Lübeck, Germany.
  • Wallentin L; University Heart Center Lübeck, 23562, Lübeck, Germany.
  • Franks PW; Deutsches Herzzentrum München, Technische Universität München, 80636, München, Germany.
  • Salomaa V; University of Michigan, Dept of Biostatistics, 1415 Washington Hts, Ann Arbor, MI, 48104, USA.
  • Dehghan A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, 70210, Kuopio, Finland.
  • Meitinger T; Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center Mainz, Mainz, Germany.
  • Samani NJ; Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.
  • Asselbergs FW; DZHK (German Center for Cardiovascular Research), Partner Site RhineMain, Mainz, Germany.
  • Erdmann J; DZHK (German Research Center for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562, Lübeck, Germany.
  • Schunkert H; Department of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, Hamburg, Germany.
Sci Rep ; 7(1): 10252, 2017 08 31.
Article em En | MEDLINE | ID: mdl-28860667
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Farmacogenética / Inibidores de Ciclo-Oxigenase 2 / Cardiotoxicidade Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Farmacogenética / Inibidores de Ciclo-Oxigenase 2 / Cardiotoxicidade Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article