In memory of Norman Bowery (1944-2016).
Curr Opin Pharmacol
; 35: 89-93, 2017 08.
Article
em En
| MEDLINE
| ID: mdl-28864032
ABSTRACT
This article is in memory of Professor Norman Bowery (1944-2016). Norman was a pharmacologist who spent most of his career researching the pharmacology of γ-aminobutyric acid (GABA). He discovered a novel metabotropic receptor subtype, GABAB, that is pharmacologically, and structurally different from the original ionotropic receptor now designated as GABAA. In his research he also studied the neurotransmitters glutamate and substance P, two molecules whose release in parts of the spinal cord is inhibited by baclofen a GABAB receptor agonist. Norman was interested in the therapeutic potential of interacting with the GABAB receptor, in particular spasticity, pain and absence epilepsy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Farmacologia
/
Receptores de GABA-B
Idioma:
En
Revista:
Curr Opin Pharmacol
Ano de publicação:
2017
Tipo de documento:
Article