<i>TOP1MT</i> deficiency promotes GC invasion and migration via the enhancements of LDHA expression and aerobic glycolysis.

Wang, Hongqiang; Zhou, Rui; Sun, Li; Xia, Jianling; Yang, Xuchun; Pan, Changqie; Huang, Na; Shi, Min; Bin, Jianping; Liao, Yulin; Liao, Wangjun

TOP1MT deficiency promotes GC invasion and migration via the enhancements of LDHA expression and aerobic glycolysis.

Wang, Hongqiang; Zhou, Rui; Sun, Li; Xia, Jianling; Yang, Xuchun; Pan, Changqie; Huang, Na; Shi, Min; Bin, Jianping; Liao, Yulin; Liao, Wangjun.

Afiliação

Wang H; Department of OncologyNanfang Hospital, Southern Medical University, Guangzhou, China.
Zhou R; Department of OncologyZhoushan Hospital, Zhoushan, China.
Sun L; Department of OncologyNanfang Hospital, Southern Medical University, Guangzhou, China.
Xia J; Department of OncologyNanfang Hospital, Southern Medical University, Guangzhou, China.
Yang X; Department of OncologyNanfang Hospital, Southern Medical University, Guangzhou, China.
Pan C; Department of OncologyZhoushan Hospital, Zhoushan, China.
Huang N; Department of OncologyNanfang Hospital, Southern Medical University, Guangzhou, China.
Shi M; Department of OncologyNanfang Hospital, Southern Medical University, Guangzhou, China.
Bin J; Department of OncologyNanfang Hospital, Southern Medical University, Guangzhou, China.
Liao Y; Department of CardiologyNanfang Hospital, Southern Medical University, Guangzhou, China.
Liao W; Department of CardiologyNanfang Hospital, Southern Medical University, Guangzhou, China.

Endocr Relat Cancer ; 24(11): 565-578, 2017 11.

Article em En | MEDLINE | ID: mdl-28874393

Assuntos

DNA Topoisomerases Tipo I/metabolismo; Neoplasias Gástricas/metabolismo; Neoplasias Gástricas/patologia; Trifosfato de Adenosina/metabolismo; Aerobiose; Animais; Linhagem Celular Tumoral; Movimento Celular; DNA Topoisomerases Tipo I/genética; Feminino; Glucose/metabolismo; Glicólise; Humanos; Isoenzimas/metabolismo; L-Lactato Desidrogenase/metabolismo; Lactato Desidrogenase 5; Ácido Láctico/metabolismo; Camundongos Nus; Mitocôndrias/metabolismo; RNA Interferente Pequeno/genética; Neoplasias Gástricas/genética; Carga Tumoral; Cicatrização

Palavras-chave

gastric cancer; glycolysis; lactate dehydrogenase A; mitochondrial topoisomerase I

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / DNA Topoisomerases Tipo I Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Endocr Relat Cancer Ano de publicação: 2017 Tipo de documento: Article

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