Accurate immune repertoire sequencing reveals malaria infection driven antibody lineage diversification in young children.

Wendel, Ben S; He, Chenfeng; Qu, Mingjuan; Wu, Di; Hernandez, Stefany M; Ma, Ke-Yue; Liu, Eugene W; Xiao, Jun; Crompton, Peter D; Pierce, Susan K; Ren, Pengyu; Chen, Keke; Jiang, Ning

Wendel, Ben S; He, Chenfeng; Qu, Mingjuan; Wu, Di; Hernandez, Stefany M; Ma, Ke-Yue; Liu, Eugene W; Xiao, Jun; Crompton, Peter D; Pierce, Susan K; Ren, Pengyu; Chen, Keke; Jiang, Ning.

Afiliação

Wendel BS; McKetta Department of Chemical Engineering, Cockrell School of Engineering, University of Texas at Austin, Austin, TX, 78712, USA.
He C; Department of Biomedical engineering, Cockrell School of Engineering, University of Texas at Austin, Austin, TX, 78712, USA.
Qu M; Department of Biomedical engineering, Cockrell School of Engineering, University of Texas at Austin, Austin, TX, 78712, USA.
Wu D; School of Life Sciences, Ludong University, Yantai, Shandong, 264025, China.
Hernandez SM; Department of Biomedical engineering, Cockrell School of Engineering, University of Texas at Austin, Austin, TX, 78712, USA.
Ma KY; McKetta Department of Chemical Engineering, Cockrell School of Engineering, University of Texas at Austin, Austin, TX, 78712, USA.
Liu EW; Institute for Cellular and Molecular Biology, College of Natural Sciences, University of Texas at Austin, Austin, TX, 78712, USA.
Xiao J; Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
Crompton PD; Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Atlanta, 30329, GA, USA.
Pierce SK; ImmuDX, LLC, Austin, TX, 78750, USA.
Ren P; Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
Chen K; Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
Jiang N; Department of Biomedical engineering, Cockrell School of Engineering, University of Texas at Austin, Austin, TX, 78712, USA.

Nat Commun ; 8(1): 531, 2017 09 14.

Article em En | MEDLINE | ID: mdl-28912592

Assuntos

Anticorpos/imunologia; Linfócitos B/imunologia; Imunoglobulina M/genética; Malária/imunologia; Análise de Sequência de DNA/métodos; Hipermutação Somática de Imunoglobulina; Pré-Escolar; Humanos; Memória Imunológica; Lactente; Mali; Recombinação V(D)J/genética

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Imunoglobulina M / Linfócitos B / Análise de Sequência de DNA / Hipermutação Somática de Imunoglobulina / Malária / Anticorpos Limite: Child, preschool / Humans / Infant País/Região como assunto: Africa Idioma: En Revista: Nat Commun Ano de publicação: 2017 Tipo de documento: Article

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