Characterization of Ca<sub>V</sub>1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and Ca<sub>V</sub>1.2 exon 33 expressions in human heart failure.

Wang, Juejin; Li, Guang; Yu, Dejie; Wong, Yuk Peng; Yong, Tan Fong; Liang, Mui Cheng; Liao, Ping; Foo, Roger; Hoppe, Uta C; Soong, Tuck Wah

Characterization of Ca_V1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and Ca_V1.2 exon 33 expressions in human heart failure.

Wang, Juejin; Li, Guang; Yu, Dejie; Wong, Yuk Peng; Yong, Tan Fong; Liang, Mui Cheng; Liao, Ping; Foo, Roger; Hoppe, Uta C; Soong, Tuck Wah.

Afiliação

Wang J; a Department of Physiology , National University of Singapore , Singapore.
Li G; b Department of Physiology , Nanjing Medical University , Nanjing , P.R. China.
Yu D; a Department of Physiology , National University of Singapore , Singapore.
Wong YP; c Key Laboratory of Medical Electrophysiology , Ministry of Education, Institute of Cardiovascular Research, Southwest Medical University , Luzhou , P.R. China.
Yong TF; a Department of Physiology , National University of Singapore , Singapore.
Liang MC; a Department of Physiology , National University of Singapore , Singapore.
Liao P; a Department of Physiology , National University of Singapore , Singapore.
Foo R; a Department of Physiology , National University of Singapore , Singapore.
Hoppe UC; d National Neuroscience Institute , Singapore.
Soong TW; e Genome Institute of Singapore , Singapore.

Channels (Austin) ; 12(1): 51-57, 2018 01 01.

Article em En | MEDLINE | ID: mdl-28949795

Assuntos

Canais de Cálcio Tipo L/genética; Éxons/genética; Insuficiência Cardíaca/genética; Fatores de Processamento de RNA/genética; Animais; Canais de Cálcio Tipo L/deficiência; Canais de Cálcio Tipo L/metabolismo; Insuficiência Cardíaca/metabolismo; Humanos; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Fatores de Processamento de RNA/metabolismo; Reação em Cadeia da Polimerase em Tempo Real

Palavras-chave

CaV1.2 calcium channel; Rbfox; alternative splicing; cardiomyopathy; heterozygous knockout

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Éxons / Canais de Cálcio Tipo L / Fatores de Processamento de RNA / Insuficiência Cardíaca Limite: Animals / Humans Idioma: En Revista: Channels (Austin) Ano de publicação: 2018 Tipo de documento: Article

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