Clinical efficacy of a new, enhanced-potency, inactivated poliovirus vaccine.
Lancet
; 1(8591): 897-9, 1988 Apr 23.
Article
em En
| MEDLINE
| ID: mdl-2895828
ABSTRACT
The 1986-87 outbreak of paralytic poliomyelitis in Senegal, with 676 reported cases, provided an opportunity to evaluate the efficacy of an enhanced-potency inactivated poliovirus vaccine (N-IPV) in the Kolda region, where this vaccine has been used since 1980. 89 cases, confirmed to have poliomyelitis with residual paralysis, were enrolled in a case-control study, up to 5 matched controls being obtained for each case. The clinical efficacy for one dose of N-IPV was 36% (95% confidence interval 0%, 67%) and for two doses was 89% (95% CI 62%, 97%).
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Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Poliomielite
/
Toxoide Diftérico
/
Toxoide Tetânico
/
Vacina contra Coqueluche
/
Vacina Antipólio de Vírus Inativado
/
Vacina contra Difteria, Tétano e Coqueluche
/
Surtos de Doenças
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
País/Região como assunto:
Africa
Idioma:
En
Revista:
Lancet
Ano de publicação:
1988
Tipo de documento:
Article