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A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines.
Gönen, Mehmet; Weir, Barbara A; Cowley, Glenn S; Vazquez, Francisca; Guan, Yuanfang; Jaiswal, Alok; Karasuyama, Masayuki; Uzunangelov, Vladislav; Wang, Tao; Tsherniak, Aviad; Howell, Sara; Marbach, Daniel; Hoff, Bruce; Norman, Thea C; Airola, Antti; Bivol, Adrian; Bunte, Kerstin; Carlin, Daniel; Chopra, Sahil; Deran, Alden; Ellrott, Kyle; Gopalacharyulu, Peddinti; Graim, Kiley; Kaski, Samuel; Khan, Suleiman A; Newton, Yulia; Ng, Sam; Pahikkala, Tapio; Paull, Evan; Sokolov, Artem; Tang, Hao; Tang, Jing; Wennerberg, Krister; Xie, Yang; Zhan, Xiaowei; Zhu, Fan; Aittokallio, Tero; Mamitsuka, Hiroshi; Stuart, Joshua M; Boehm, Jesse S; Root, David E; Xiao, Guanghua; Stolovitzky, Gustavo; Hahn, William C; Margolin, Adam A.
Afiliação
  • Gönen M; Department of Industrial Engineering, College of Engineering, Koç University, Istanbul, Turkey; School of Medicine, Koç University, Istanbul, Turkey; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA.
  • Weir BA; Cancer Program, The Broad Institute, Boston, MA, USA.
  • Cowley GS; Genetic Perturbation Platform, The Broad Institute, Boston, MA, USA; Janssen R&D US, Spring House, PA, USA.
  • Vazquez F; Cancer Program, The Broad Institute, Boston, MA, USA; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Guan Y; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Jaiswal A; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.
  • Karasuyama M; Department of Computer Science, Nagoya Institute of Technology, Nagoya, Japan.
  • Uzunangelov V; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • Wang T; Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Tsherniak A; Cancer Program, The Broad Institute, Boston, MA, USA.
  • Howell S; Cancer Program, The Broad Institute, Boston, MA, USA; Brandeis University, Waltham, MA, USA.
  • Marbach D; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Hoff B; Sage Bionetworks, Seattle, WA, USA.
  • Norman TC; Sage Bionetworks, Seattle, WA, USA.
  • Airola A; Department of Information Technology, University of Turku, Turku, Finland.
  • Bivol A; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • Bunte K; Helsinki Institute for Information Technology HIIT, Department of Computer Science, Aalto University, Espoo, Finland; School of Computer Science, The University of Birmingham, Birmingham, UK.
  • Carlin D; Department of Bioengineering, University of California, San Diego, CA, USA.
  • Chopra S; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA; Department of Computer Science, Stanford University, Stanford, CA, USA.
  • Deran A; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • Ellrott K; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • Gopalacharyulu P; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.
  • Graim K; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • Kaski S; Helsinki Institute for Information Technology HIIT, Department of Computer Science, Aalto University, Espoo, Finland; Helsinki Institute for Information Technology HIIT, Department of Computer Science, University of Helsinki, Helsinki, Finland.
  • Khan SA; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.
  • Newton Y; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • Ng S; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • Pahikkala T; Department of Information Technology, University of Turku, Turku, Finland.
  • Paull E; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • Sokolov A; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • Tang H; Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Tang J; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.
  • Wennerberg K; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.
  • Xie Y; Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA; Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USA; Simons Comprehensive Cancer Center, University of Texas Southwes
  • Zhan X; Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Zhu F; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Aittokallio T; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland; Department of Mathematics and Statistics, University of Turku, Turku, Finland.
  • Mamitsuka H; Bioinformatics Center, Institute for Chemical Research, Kyoto University, Kyoto, Japan.
  • Stuart JM; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • Boehm JS; Cancer Program, The Broad Institute, Boston, MA, USA.
  • Root DE; Genetic Perturbation Platform, The Broad Institute, Boston, MA, USA.
  • Xiao G; Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA; Simons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Stolovitzky G; Computational Biology Center, IBM Thomas J. Watson Research Center, Yorktown Heights, NY, USA; Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: gustavo@us.ibm.com.
  • Hahn WC; Cancer Program, The Broad Institute, Boston, MA, USA; Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address: william_hahn@dfci.harvard.edu.
  • Margolin AA; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA; Computational Biology Program, Oregon Health & Science University, Portland, OR, USA. Electronic address: margolin@ohsu.edu.
Cell Syst ; 5(5): 485-497.e3, 2017 11 22.
Article em En | MEDLINE | ID: mdl-28988802
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Expressão Gênica / Genes Essenciais Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Cell Syst Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Expressão Gênica / Genes Essenciais Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Cell Syst Ano de publicação: 2017 Tipo de documento: Article