Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR&#945; immune cell receptor.

Furukawa, Atsushi; Kakita, Kosuke; Yamada, Tomoki; Ishizuka, Mikihiro; Sakamoto, Jiro; Hatori, Nanao; Maeda, Naoyoshi; Ohsaka, Fumina; Saitoh, Takashi; Nomura, Takao; Kuroki, Kimiko; Nambu, Hisanori; Arase, Hisashi; Matsunaga, Shigeki; Anada, Masahiro; Ose, Toyoyuki; Hashimoto, Shunichi; Maenaka, Katsumi

Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILRα immune cell receptor.

Furukawa, Atsushi; Kakita, Kosuke; Yamada, Tomoki; Ishizuka, Mikihiro; Sakamoto, Jiro; Hatori, Nanao; Maeda, Naoyoshi; Ohsaka, Fumina; Saitoh, Takashi; Nomura, Takao; Kuroki, Kimiko; Nambu, Hisanori; Arase, Hisashi; Matsunaga, Shigeki; Anada, Masahiro; Ose, Toyoyuki; Hashimoto, Shunichi; Maenaka, Katsumi.

Afiliação

Furukawa A; From the Laboratories of Biomolecular Science and.
Kakita K; Synthetic and Industrial Chemistry, Faculty of Pharmaceutical Sciences and.
Yamada T; Center for Research and Education on Drug Discovery, Hokkaido University, Sapporo 060-0812, Japan and.
Ishizuka M; From the Laboratories of Biomolecular Science and.
Sakamoto J; From the Laboratories of Biomolecular Science and.
Hatori N; Synthetic and Industrial Chemistry, Faculty of Pharmaceutical Sciences and.
Maeda N; Center for Research and Education on Drug Discovery, Hokkaido University, Sapporo 060-0812, Japan and.
Ohsaka F; Center for Research and Education on Drug Discovery, Hokkaido University, Sapporo 060-0812, Japan and.
Saitoh T; Center for Research and Education on Drug Discovery, Hokkaido University, Sapporo 060-0812, Japan and.
Nomura T; Center for Research and Education on Drug Discovery, Hokkaido University, Sapporo 060-0812, Japan and.
Kuroki K; From the Laboratories of Biomolecular Science and.
Nambu H; Synthetic and Industrial Chemistry, Faculty of Pharmaceutical Sciences and.
Arase H; World Premier International Immunology Frontier Research Center and.
Matsunaga S; Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.
Anada M; Synthetic and Industrial Chemistry, Faculty of Pharmaceutical Sciences and.
Ose T; Synthetic and Industrial Chemistry, Faculty of Pharmaceutical Sciences and.
Hashimoto S; From the Laboratories of Biomolecular Science and.
Maenaka K; Synthetic and Industrial Chemistry, Faculty of Pharmaceutical Sciences and.

J Biol Chem ; 292(51): 21128-21136, 2017 12 22.

Article em En | MEDLINE | ID: mdl-29046357

Assuntos

Glicoproteínas de Membrana/metabolismo; Modelos Moleculares; Fragmentos de Peptídeos/metabolismo; Receptores Imunológicos/metabolismo; Proteínas do Envelope Viral/metabolismo; Acetilgalactosamina/análogos & derivados; Acetilgalactosamina/química; Acetilgalactosamina/metabolismo; Sítios de Ligação; Calorimetria; Cristalografia por Raios X; Escherichia coli/metabolismo; Humanos; Cinética; Ligantes; Glicoproteínas de Membrana/química; Glicoproteínas de Membrana/genética; Fragmentos de Peptídeos/síntese química; Fragmentos de Peptídeos/química; Fragmentos de Peptídeos/genética; Polissacarídeos/síntese química; Polissacarídeos/química; Polissacarídeos/metabolismo; Conformação Proteica; Domínios e Motivos de Interação entre Proteínas; Receptores Imunológicos/química; Receptores Imunológicos/genética; Proteínas Recombinantes; Estereoisomerismo; Termodinâmica; Proteínas do Envelope Viral/síntese química; Proteínas do Envelope Viral/química

Palavras-chave

X-ray crystallography; cell surface receptor; immunology; isothermal titration calorimetry (ITC); protein chemistry; protein structure

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Glicoproteínas de Membrana / Receptores Imunológicos / Modelos Moleculares / Proteínas do Envelope Viral Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2017 Tipo de documento: Article

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