In Vivo Pulmonary Delivery and Magnetic-Targeting of Dry Powder Nano-in-Microparticles.

Price, Dominique N; Stromberg, Loreen R; Kunda, Nitesh K; Muttil, Pavan

Price, Dominique N; Stromberg, Loreen R; Kunda, Nitesh K; Muttil, Pavan.

Afiliação

Price DN; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center , Albuquerque, New Mexico 87131, United States.
Stromberg LR; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center , Albuquerque, New Mexico 87131, United States.
Kunda NK; Department of Mechanical Engineering, Iowa State University , Ames, Iowa 50011, United States.
Muttil P; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center , Albuquerque, New Mexico 87131, United States.

Mol Pharm ; 14(12): 4741-4750, 2017 12 04.

Article em En | MEDLINE | ID: mdl-29068693

Assuntos

Doxorrubicina/administração & dosagem; Portadores de Fármacos/química; Compostos Férricos/química; Nanopartículas de Magnetita/química; Células A549; Aerossóis; Animais; Humanos; Pulmão/efeitos dos fármacos; Pulmão/metabolismo; Campos Magnéticos; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Modelos Animais; Nanosferas/química; Pós; Traqueia/efeitos dos fármacos; Traqueia/metabolismo

Palavras-chave

aerosolized drug delivery; nano-in-microparticles (NIMs); non-small cell lung cancer; pulmonary chemotherapeutic; superparamagnetic iron oxide nanoparticles (SPIONs); targeted pulmonary delivery

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Portadores de Fármacos / Compostos Férricos / Doxorrubicina / Nanopartículas de Magnetita Limite: Animals / Humans / Male Idioma: En Revista: Mol Pharm Ano de publicação: 2017 Tipo de documento: Article

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