Clostridium difficile colitis secondary to intravenous vancomycin.
Dig Dis Sci
; 34(1): 148-9, 1989 Jan.
Article
em En
| MEDLINE
| ID: mdl-2910675
ABSTRACT
Nearly every known antibiotic has been implicated as a cause of Clostridium difficile colitis. We report the first case resulting from monotherapy with intravenous vancomycin. The patient was on chronic hemodialysis and was treated with intravenous vancomycin for presumed cervical osteomyelitis. After 29 days of therapy he developed abdominal pain and diarrhea and his stool was found to contain both C. difficile and cytotoxin. The patient responded with symptomatic and microbiological recovery to withdrawal of the drug and treatment with oral metronidazole. The prolonged elevation of serum vancomycin levels in patients with renal failure may predispose them to the development of C. difficile colitis.
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Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Enterocolite Pseudomembranosa
/
Vancomicina
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Dig Dis Sci
Ano de publicação:
1989
Tipo de documento:
Article