Reduced dorsolateral prefrontal cortex activation during affective Go/NoGo in violent schizophrenia patients: An fMRI study.
Schizophr Res
; 197: 249-252, 2018 07.
Article
em En
| MEDLINE
| ID: mdl-29129509
ABSTRACT
We investigated the influence of anger processing on cognitive control in male schizophrenia patients presenting violent behaviors. We recruited 23 patients without and 24 patients with (SCZ+V) a history of violent behaviors, as well as 22 healthy non-violent men. Participants were administered an affective (angry-neutral faces) Go/NoGo task while undergoing functional magnetic resonance imaging. We found a reduced activation in the dorsolateral prefrontal cortex in SCZ+V patients specifically when inhibiting a response while viewing angry faces. These results show an inability of SCZ+V to recruit a core region of the (inhibitory) cognitive control network in the context of anger.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esquizofrenia
/
Violência
/
Córtex Pré-Frontal
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Expressão Facial
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Função Executiva
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Neuroimagem Funcional
/
Inibição Psicológica
/
Ira
Aspecto:
Determinantes_sociais_saude
Limite:
Adolescent
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Adult
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Schizophr Res
Ano de publicação:
2018
Tipo de documento:
Article