Birth, coming of age and death: The intriguing life of long noncoding RNAs.
Semin Cell Dev Biol
; 79: 143-152, 2018 07.
Article
em En
| MEDLINE
| ID: mdl-29133230
ABSTRACT
Mammalian genomes are pervasively transcribed, with long noncoding RNAs being the most abundant fraction. Recent studies have highlighted the central role played by these transcripts in several physiological and pathological processes. Despite several metabolic features shared between coding and noncoding transcripts, these two classes of RNAs exhibit multiple differences regarding their biogenesis and processing. Here we review such distinctions, focusing on the unique features of specific long noncoding RNAs.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Precursores de RNA
/
Processamento Pós-Transcricional do RNA
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Genoma
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RNA Longo não Codificante
Limite:
Animals
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Humans
Idioma:
En
Revista:
Semin Cell Dev Biol
Ano de publicação:
2018
Tipo de documento:
Article