Influence of process parameters on the effectiveness of photooxidative treatment of pharmaceuticals.
J Environ Sci Health A Tox Hazard Subst Environ Eng
; 53(4): 338-351, 2018 Mar 21.
Article
em En
| MEDLINE
| ID: mdl-29173087
ABSTRACT
In this study, UV-C/H2O2 and UV-C/[Formula see text] processes as photooxidative Advanced oxidation processes were applied for the treatment of seven pharmaceuticals, either already included in the Directive 2013/39/EU "watch list" (17α- ethynylestradiol, 17ß-estradiol) or with potential to be added in the near future due to environmental properties and increasing consumption (azithromycin, carbamazepine, dexamethasone, erythromycin and oxytetracycline). The influence of process parameters (pH, oxidant concentration and type) on the pharmaceuticals degradation was studied through employed response surface modelling approach. It was established that degradation obeys first-order kinetic regime regardless structural differences and over entire range of studied process parameters. The results revealed that the effectiveness of UV-C/H2O2 process is highly dependent on both initial pH and oxidant concentration. It was found that UV-C/[Formula see text] process, exhibiting several times faster degradation of studied pharmaceuticals, is less sensitive to pH changes providing practical benefit to its utilization. The influence of water matrix on degradation kinetics of studied pharmaceuticals was studied through natural organic matter effects on single component and mixture systems.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Raios Ultravioleta
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Poluentes Químicos da Água
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Preparações Farmacêuticas
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Oxidantes
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Purificação da Água
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Peróxido de Hidrogênio
Tipo de estudo:
Guideline
Idioma:
En
Revista:
J Environ Sci Health A Tox Hazard Subst Environ Eng
Ano de publicação:
2018
Tipo de documento:
Article