The aPKC-CBP Pathway Regulates Post-stroke Neurovascular Remodeling and Functional Recovery.

Gouveia, Ayden; Seegobin, Matthew; Kannangara, Timal S; He, Ling; Wondisford, Fredric; Comin, Cesar H; Costa, Luciano da F; Béïque, Jean-Claude; Lagace, Diane C; Lacoste, Baptiste; Wang, Jing

Gouveia, Ayden; Seegobin, Matthew; Kannangara, Timal S; He, Ling; Wondisford, Fredric; Comin, Cesar H; Costa, Luciano da F; Béïque, Jean-Claude; Lagace, Diane C; Lacoste, Baptiste; Wang, Jing.

Afiliação

Gouveia A; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Seegobin M; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
Kannangara TS; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada; Canadian Partnership for Stroke Recovery, Ottawa, ON, Canada.
He L; Department of Pediatrics and Medicine, Johns Hopkins Medical School, Baltimore, MD, USA.
Wondisford F; Department of Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Comin CH; Department of Computer Science, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
Costa LDF; São Carlos Institute of Physics, University of São Paulo, PO Box 369, São Carlos, São Paulo 13560-970, Brazil.
Béïque JC; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada; University of Ottawa Brain and Mind Research Institute, Ottawa, ON, Canada; Neuroscience Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada; Canadian Partnership for Stroke Reco
Lagace DC; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada; University of Ottawa Brain and Mind Research Institute, Ottawa, ON, Canada; Neuroscience Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada; Canadian Partnership for Stroke Reco
Lacoste B; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada; University of Ottawa Brain and Mind Research Institute, Ottawa, ON, Canada; Neuroscience Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada; Canadian Partnership for Stroke Reco
Wang J; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada; University of Ottawa Brain and Mind Research Institute, Ottawa, ON, Canada; Canadian Partnershi

Stem Cell Reports ; 9(6): 1735-1744, 2017 12 12.

Article em En | MEDLINE | ID: mdl-29173896

Assuntos

Proteína de Ligação a CREB/genética; Proteína Quinase C/genética; Acidente Vascular Cerebral/genética; Remodelação Vascular/genética; Animais; Isquemia Encefálica/genética; Isquemia Encefálica/patologia; Isquemia Encefálica/reabilitação; Reprogramação Celular/genética; Camundongos; Neurogênese/genética; Pericitos/metabolismo; Pericitos/patologia; Fosforilação; Recuperação de Função Fisiológica/genética; Transdução de Sinais/genética; Acidente Vascular Cerebral/fisiopatologia; Reabilitação do Acidente Vascular Cerebral/métodos

Palavras-chave

aPKC-CBP pathway; cellular reprogramming; ischemic stroke; neural precursors; pericyte; vascular remodeling

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Acidente Vascular Cerebral / Proteína de Ligação a CREB / Remodelação Vascular Limite: Animals Idioma: En Revista: Stem Cell Reports Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google