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Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth.
Van Helleputte, Lawrence; Kater, Mandy; Cook, Dana P; Eykens, Caroline; Rossaert, Elisabeth; Haeck, Wanda; Jaspers, Tom; Geens, Natasja; Vanden Berghe, Pieter; Gysemans, Conny; Mathieu, Chantal; Robberecht, Wim; Van Damme, Philip; Cavaletti, Guido; Jarpe, Matthew; Van Den Bosch, Ludo.
Afiliação
  • Van Helleputte L; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Kater M; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Cook DP; KU Leuven - University of Leuven, Clinical and Experimental Endocrinology, Leuven, Belgium.
  • Eykens C; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Rossaert E; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Haeck W; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Jaspers T; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Geens N; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Vanden Berghe P; KU Leuven - University of Leuven, Laboratory for Enteric Neuroscience, TARGID, Leuven, Belgium.
  • Gysemans C; KU Leuven - University of Leuven, Clinical and Experimental Endocrinology, Leuven, Belgium.
  • Mathieu C; KU Leuven - University of Leuven, Clinical and Experimental Endocrinology, Leuven, Belgium.
  • Robberecht W; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium; University Hospitals Leuven, Department of
  • Van Damme P; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium; University Hospitals Leuven, Department of
  • Cavaletti G; Experimental Neurology Unit and Milan Center for Neuroscience, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Jarpe M; Acetylon Pharmaceuticals Inc., Boston, MA, USA.
  • Van Den Bosch L; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium. Electronic address: ludo.vandenbosch@kuleu
Neurobiol Dis ; 111: 59-69, 2018 03.
Article em En | MEDLINE | ID: mdl-29197621
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vincristina / Doenças do Sistema Nervoso Periférico / Fármacos Neuroprotetores / Desacetilase 6 de Histona / Neoplasias / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neurobiol Dis Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vincristina / Doenças do Sistema Nervoso Periférico / Fármacos Neuroprotetores / Desacetilase 6 de Histona / Neoplasias / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neurobiol Dis Ano de publicação: 2018 Tipo de documento: Article