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Hypertrophic cardiomyopathy-linked mutation in troponin T causes myofibrillar disarray and pro-arrhythmic action potential changes in human iPSC cardiomyocytes.
Wang, Lili; Kim, Kyungsoo; Parikh, Shan; Cadar, Adrian Gabriel; Bersell, Kevin R; He, Huan; Pinto, Jose R; Kryshtal, Dmytro O; Knollmann, Bjorn C.
Afiliação
  • Wang L; Division of Clinical Pharmacology, Vanderbilt Univ Medical Ctr, Nashville, TN, Medical Research Building IV, Rm.1275, 2215B Garland Ave, Nashville, TN 37232, USA.
  • Kim K; Division of Clinical Pharmacology, Vanderbilt Univ Medical Ctr, Nashville, TN, Medical Research Building IV, Rm.1275, 2215B Garland Ave, Nashville, TN 37232, USA.
  • Parikh S; Division of Clinical Pharmacology, Vanderbilt Univ Medical Ctr, Nashville, TN, Medical Research Building IV, Rm.1275, 2215B Garland Ave, Nashville, TN 37232, USA.
  • Cadar AG; Division of Cardiovascular Medicine, Vanderbilt Univ Medical Ctr, Nashville, TN, Light Hall 1155A, 2215B Garland Ave, Nashville, TN 37232, USA.
  • Bersell KR; Division of Clinical Pharmacology, Vanderbilt Univ Medical Ctr, Nashville, TN, Medical Research Building IV, Rm.1275, 2215B Garland Ave, Nashville, TN 37232, USA.
  • He H; Institute of Molecular Biophysics, Florida State University, 91 Chieftan Way, Tallahassee, FL 32306, USA; Translational Science Laboratory, Florida State University College of Medicine, 1115 W. Call Street, Tallahassee, FL 32306, USA.
  • Pinto JR; Department of Biomedical Sciences, Florida State University College of Medicine, 1115 W. Call Street, Tallahassee, FL 32306, USA.
  • Kryshtal DO; Division of Clinical Pharmacology, Vanderbilt Univ Medical Ctr, Nashville, TN, Medical Research Building IV, Rm.1275, 2215B Garland Ave, Nashville, TN 37232, USA. Electronic address: dmytro.o.kryshtal@Vanderbilt.Edu.
  • Knollmann BC; Division of Clinical Pharmacology, Vanderbilt Univ Medical Ctr, Nashville, TN, Medical Research Building IV, Rm.1275, 2215B Garland Ave, Nashville, TN 37232, USA. Electronic address: bjorn.knollmann@vanderbilt.edu.
J Mol Cell Cardiol ; 114: 320-327, 2018 01.
Article em En | MEDLINE | ID: mdl-29217433
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Cardiomiopatia Hipertrófica / Potenciais de Ação / Troponina T / Miócitos Cardíacos / Células-Tronco Pluripotentes Induzidas / Mutação / Miofibrilas Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Revista: J Mol Cell Cardiol Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Cardiomiopatia Hipertrófica / Potenciais de Ação / Troponina T / Miócitos Cardíacos / Células-Tronco Pluripotentes Induzidas / Mutação / Miofibrilas Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Revista: J Mol Cell Cardiol Ano de publicação: 2018 Tipo de documento: Article