Female fertility preservation in the pediatric and adolescent cancer patient population.
Best Pract Res Clin Obstet Gynaecol
; 48: 147-157, 2018 Apr.
Article
em En
| MEDLINE
| ID: mdl-29221705
The 5-year survival rate for childhood cancer is over 80%, thereby increasing the number of young women facing infertility in the future because of the gonadotoxic effects of chemotherapy and radiation. The gonadotoxic effects of childhood cancer treatment vary by the radiation regimen and the chemotherapeutic drugs utilized. Although the American Society of Clinical Oncology guidelines recommend fertility preservation for all patients, there are several barriers and ethical considerations to fertility preservation in the pediatric and adolescent female population. Additionally, the fertility preservation methods for pre- and postpubertal females differ, with only experimental methods available for prepubertal females. We will review the risk of chemotherapy and radiation on female fertility, the approach to fertility preservation in the pediatric and adolescent female population, methods of fertility preservation for both pre- and postpubertal females, barriers to fertility preservation, cost, and psychological and ethical considerations.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Radioterapia
/
Preservação da Fertilidade
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Antineoplásicos
Tipo de estudo:
Etiology_studies
/
Guideline
Aspecto:
Ethics
Limite:
Adolescent
/
Child
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Female
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Humans
Idioma:
En
Revista:
Best Pract Res Clin Obstet Gynaecol
Ano de publicação:
2018
Tipo de documento:
Article