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Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.
Baker, Ann-Marie; Huang, Weini; Wang, Xiao-Ming Mindy; Jansen, Marnix; Ma, Xiao-Jun; Kim, Jeffrey; Anderson, Courtney M; Wu, Xingyong; Pan, Liuliu; Su, Nan; Luo, Yuling; Domingo, Enric; Heide, Timon; Sottoriva, Andrea; Lewis, Annabelle; Beggs, Andrew D; Wright, Nicholas A; Rodriguez-Justo, Manuel; Park, Emily; Tomlinson, Ian; Graham, Trevor A.
Afiliação
  • Baker AM; Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK. a.m.c.baker@qmul.ac.uk.
  • Huang W; Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.
  • Wang XM; Advanced Cell Diagnostics, Newark, CA, 94560, USA.
  • Jansen M; Department of Histopathology, University College London Hospital, London, WC1E 6JJ, UK.
  • Ma XJ; UCL Cancer Institute, University College London, London, WC1E 6DD, UK.
  • Kim J; Advanced Cell Diagnostics, Newark, CA, 94560, USA.
  • Anderson CM; Advanced Cell Diagnostics, Newark, CA, 94560, USA.
  • Wu X; Advanced Cell Diagnostics, Newark, CA, 94560, USA.
  • Pan L; Advanced Cell Diagnostics, Newark, CA, 94560, USA.
  • Su N; Advanced Cell Diagnostics, Newark, CA, 94560, USA.
  • Luo Y; Advanced Cell Diagnostics, Newark, CA, 94560, USA.
  • Domingo E; Advanced Cell Diagnostics, Newark, CA, 94560, USA.
  • Heide T; Department of Oncology, Old Road Campus Research Building, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Sottoriva A; Centre for Evolution and Cancer, The Institute of Cancer Research, 15 Cotswold Road, Sutton, London, SM2 5NG, UK.
  • Lewis A; Centre for Evolution and Cancer, The Institute of Cancer Research, 15 Cotswold Road, Sutton, London, SM2 5NG, UK.
  • Beggs AD; Cancer Gene Regulation Laboratory, Centre for Cancer Gene Research, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK.
  • Wright NA; Surgical Research Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Rodriguez-Justo M; Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.
  • Park E; Department of Histopathology, University College London Hospital, London, WC1E 6JJ, UK.
  • Tomlinson I; Advanced Cell Diagnostics, Newark, CA, 94560, USA.
  • Graham TA; Cancer Genetics and Evolution Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, B15 2TT, UK. i.tomlinson@bham.ac.uk.
Nat Commun ; 8(1): 1998, 2017 12 08.
Article em En | MEDLINE | ID: mdl-29222441
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Análise Mutacional de DNA / Neoplasias Colorretais / Hibridização In Situ / Resistencia a Medicamentos Antineoplásicos / Recidiva Local de Neoplasia Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Análise Mutacional de DNA / Neoplasias Colorretais / Hibridização In Situ / Resistencia a Medicamentos Antineoplásicos / Recidiva Local de Neoplasia Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2017 Tipo de documento: Article