RANKL Signaling Sustains Primary Tumor Growth in Genetically Engineered Mouse Models of Lung Adenocarcinoma.

Faget, Julien; Contat, Caroline; Zangger, Nadine; Peters, Solange; Meylan, Etienne

Faget, Julien; Contat, Caroline; Zangger, Nadine; Peters, Solange; Meylan, Etienne.

Afiliação

Faget J; Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Contat C; Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Zangger N; Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; Bioinformatics Core Facility, Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Peters S; Department of Oncology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.
Meylan E; Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. Electronic address: etienne.meylan@epfl.ch.

J Thorac Oncol ; 13(3): 387-398, 2018 03.

Article em En | MEDLINE | ID: mdl-29223537

Assuntos

Adenocarcinoma de Pulmão/genética; Engenharia Genética/métodos; Neoplasias Pulmonares/genética; Ligante RANK/genética; Adenocarcinoma de Pulmão/patologia; Animais; Modelos Animais de Doenças; Neoplasias Pulmonares/patologia; Camundongos; Estudos Retrospectivos; Transdução de Sinais

Palavras-chave

Genetically engineered mouse models; Lung adenocarcinoma; Preclinical trial; RANK ligand

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Engenharia Genética / Ligante RANK / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: J Thorac Oncol Ano de publicação: 2018 Tipo de documento: Article

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