Measuring Oxidative Stress in Caenorhabditis elegans: Paraquat and Juglone Sensitivity Assays.
Bio Protoc
; 7(1)2017 Jan 05.
Article
em En
| MEDLINE
| ID: mdl-29276721
ABSTRACT
Oxidative stress has been proposed to be one of the main causes of aging and has been implicated in the pathogenesis of many diseases. Sensitivity to oxidative stress can be measured by quantifying survival following exposure to a reactive oxygen species (ROS)-generating compound such as paraquat or juglone. Sensitivity to oxidative stress is a balance between basal levels of ROS, the ability to detoxify ROS, and the ability to repair ROS-mediated damage.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
Bio Protoc
Ano de publicação:
2017
Tipo de documento:
Article