Study design and rationale to assess Doxycycline Efficacy in preventing coronary Artery Lesions in children with Kawasaki disease (DEAL trial) - A phase II clinical trial.

Bratincsak, Andras; Limm-Chan, Blair N; Nerurkar, Vivek R; Ching, Lauren L; Reddy, Venu D; Lim, Eunjung; Shohet, Ralph V; Melish, Marian E

Bratincsak, Andras; Limm-Chan, Blair N; Nerurkar, Vivek R; Ching, Lauren L; Reddy, Venu D; Lim, Eunjung; Shohet, Ralph V; Melish, Marian E.

Afiliação

Bratincsak A; Kapi'olani Medical Specialists, Hawai'i Pacific Health, Honolulu, HI, United States. Electronic address: andras.bratincsak@kapiolani.org.
Limm-Chan BN; Hawai'i Residency Program, University of Hawai'i, Honolulu, HI, United States.
Nerurkar VR; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, United States.
Ching LL; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, United States.
Reddy VD; Department of Pediatrics, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, United States.
Lim E; Biostatistics Core, Department of Complimentary and Integrative Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, United States.
Shohet RV; Department of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, United States.
Melish ME; Kapi'olani Medical Specialists, Hawai'i Pacific Health, Honolulu, HI, United States; Department of Pediatrics, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, United States.

Contemp Clin Trials ; 65: 33-38, 2018 02.

Article em En | MEDLINE | ID: mdl-29313803

Assuntos

Doença da Artéria Coronariana/etiologia; Doença da Artéria Coronariana/prevenção & controle; Doxiciclina/administração & dosagem; Inibidores de Metaloproteinases de Matriz/administração & dosagem; Síndrome de Linfonodos Mucocutâneos/complicações; Adolescente; Criança; Pré-Escolar; Método Duplo-Cego; Ecocardiografia; Elastina; Feminino; Humanos; Lactente; Masculino; Metaloproteinases da Matriz; Estudos Prospectivos

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Doxiciclina / Inibidores de Metaloproteinases de Matriz / Síndrome de Linfonodos Mucocutâneos Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Contemp Clin Trials Ano de publicação: 2018 Tipo de documento: Article

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