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Design, synthesis, biological evaluation and docking studies of new 3-(4,5-dihydro-1H-pyrazol/isoxazol-5-yl)-2-phenyl-1H-indole derivatives as potent antioxidants and 15-lipoxygenase inhibitors.
ElBordiny, Haydi Saher; El-Miligy, Mostafa Mahmoud; Kassab, Shaymaa Emam; Daabees, Hoda; Mohamed Ali, Waleed Ali; Abdelhamid Mohamed El-Hawash, Soad.
Afiliação
  • ElBordiny HS; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Damanhour University, Damanhour, El-Buhaira, 22516, Egypt.
  • El-Miligy MM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21526, Egypt.
  • Kassab SE; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Damanhour University, Damanhour, El-Buhaira, 22516, Egypt. Electronic address: shaymaakassab@yahoo.com.
  • Daabees H; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Damanhour University, Damanhour, El-Buhaira, 22516, Egypt.
  • Mohamed Ali WA; Biochemistry Department, General Hospital, Cairo, 11753, Egypt.
  • Abdelhamid Mohamed El-Hawash S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21526, Egypt.
Eur J Med Chem ; 145: 594-605, 2018 Feb 10.
Article em En | MEDLINE | ID: mdl-29339254
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Araquidonato 15-Lipoxigenase / Desenho de Fármacos / Inibidores de Lipoxigenase / Indóis / Antioxidantes Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Araquidonato 15-Lipoxigenase / Desenho de Fármacos / Inibidores de Lipoxigenase / Indóis / Antioxidantes Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2018 Tipo de documento: Article