[Treatment of systemic scleroderma with factor XIII in 86 patients, with long-term follow-up]. / Traitement de la sclérodermie systémique par le facteur XIII chez 86 malades suivis à long terme.
Presse Med
; 14(46): 2327-9, 1985 Dec 28.
Article
em Fr
| MEDLINE
| ID: mdl-2935830
ABSTRACT
Eighty-six patients with progressive systemic sclerosis were given coagulation factor XIII intravenously in different dosage regimens. The mean duration of treatment was 19 +/- 18 months and patients were followed up for 22.9 +/- 18.8 months. Improvement or stabilization of the lesions was obtained in 44/86 patients and exclusively concerned skin lesions; there was no improvement in visceral lesions. The drug was well tolerated in short-and long-term treatment. It is concluded that factor XIII demonstrated lasting effectiveness in one-half of the patients treated.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Escleroderma Sistêmico
/
Fator XIII
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Fr
Revista:
Presse Med
Ano de publicação:
1985
Tipo de documento:
Article