Simultaneous detection of single-nucleotide variant, deletion/insertion, and fusion in lung and thyroid carcinoma using cytology specimen and an RNA-based next-generation sequencing assay.

Guseva, Natalya V; Jaber, Omar; Stence, Aaron A; Sompallae, Krishnaveni; Bashir, Amani; Sompallae, Ramakrishna; Bossler, Aaron D; Jensen, Chris S; Ma, Deqin

Guseva, Natalya V; Jaber, Omar; Stence, Aaron A; Sompallae, Krishnaveni; Bashir, Amani; Sompallae, Ramakrishna; Bossler, Aaron D; Jensen, Chris S; Ma, Deqin.

Afiliação

Guseva NV; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Jaber O; Department of Pathology, King Hussein Cancer Center, Amman, Jordan.
Stence AA; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Sompallae K; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Bashir A; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Sompallae R; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Bossler AD; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Jensen CS; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Ma D; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.

Cancer Cytopathol ; 126(3): 158-169, 2018 03.

Article em En | MEDLINE | ID: mdl-29364576

Assuntos

Neoplasias Pulmonares/genética; Mutação; RNA Neoplásico/genética; Análise de Sequência de RNA/métodos; Neoplasias da Glândula Tireoide/genética; Fusão Gênica; Humanos; Mutação INDEL; Hibridização in Situ Fluorescente; Neoplasias Pulmonares/patologia; Polimorfismo de Nucleotídeo Único; Proto-Oncogene Mas; Neoplasias da Glândula Tireoide/patologia

Palavras-chave

fine-needle aspiration; gene fusions and mutations; lung adenocarcinoma; next-generation sequencing; thyroid carcinoma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Neoplásico / Neoplasias da Glândula Tireoide / Análise de Sequência de RNA / Neoplasias Pulmonares / Mutação Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Cancer Cytopathol Ano de publicação: 2018 Tipo de documento: Article

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