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A new cadinane sesquiterpenoid glucoside with cytotoxicity from Abelmoschus sagittifolius.
Chen, De-Li; Li, Guang; Liu, Yang-Yang; Ma, Guo-Xu; Zheng, Wei; Sun, Xiao-Bo; Xu, Xu-Dong.
Afiliação
  • Chen DL; a Hainan Branch Institute of Medicinal Plant Development (Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine) , Chinese Academy of Medical Sciences & Peking Union Medical College , Wanning , China.
  • Li G; b Yunnan Branch Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , Xishuangbanna , China.
  • Liu YY; a Hainan Branch Institute of Medicinal Plant Development (Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine) , Chinese Academy of Medical Sciences & Peking Union Medical College , Wanning , China.
  • Ma GX; a Hainan Branch Institute of Medicinal Plant Development (Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine) , Chinese Academy of Medical Sciences & Peking Union Medical College , Wanning , China.
  • Zheng W; c Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing , China.
  • Sun XB; a Hainan Branch Institute of Medicinal Plant Development (Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine) , Chinese Academy of Medical Sciences & Peking Union Medical College , Wanning , China.
  • Xu XD; c Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing , China.
Nat Prod Res ; 33(12): 1699-1704, 2019 Jun.
Article em En | MEDLINE | ID: mdl-29409349
ABSTRACT
A new cadinane sesquiterpenoid glucoside, 2ß,7,3-trihydroxycalamenene 3-O-ß-d-glucoside (1) together with six known compounds, N-(p-trans-coumaroyl)-N-methyl tyramine (2), Cleomiscosin A (3), 9,12,13-trihydroxy-10,15-heptadecadienoic acid (4), Cytochalasin B (5), Marmesinin (6) and N-(p-trans-coumaroyl) tyramine (7) were obtained from the stem bark of Abelmoschus sagittifolius. The new structure of compound 1 was elucidated by analysing its 1H and 13C-NMR, 1H-1H COSY, HSQC, HMBC, NOESY and HR-ESI-MS spectra. Compounds 1-7 showed moderate cytotoxicity against Hela and HepG-2 human cancer cell lines.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sesquiterpenos / Abelmoschus Limite: Humans Idioma: En Revista: Nat Prod Res Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sesquiterpenos / Abelmoschus Limite: Humans Idioma: En Revista: Nat Prod Res Ano de publicação: 2019 Tipo de documento: Article