A new cadinane sesquiterpenoid glucoside with cytotoxicity from Abelmoschus sagittifolius.
Nat Prod Res
; 33(12): 1699-1704, 2019 Jun.
Article
em En
| MEDLINE
| ID: mdl-29409349
ABSTRACT
A new cadinane sesquiterpenoid glucoside, 2ß,7,3-trihydroxycalamenene 3-O-ß-d-glucoside (1) together with six known compounds, N-(p-trans-coumaroyl)-N-methyl tyramine (2), Cleomiscosin A (3), 9,12,13-trihydroxy-10,15-heptadecadienoic acid (4), Cytochalasin B (5), Marmesinin (6) and N-(p-trans-coumaroyl) tyramine (7) were obtained from the stem bark of Abelmoschus sagittifolius. The new structure of compound 1 was elucidated by analysing its 1H and 13C-NMR, 1H-1H COSY, HSQC, HMBC, NOESY and HR-ESI-MS spectra. Compounds 1-7 showed moderate cytotoxicity against Hela and HepG-2 human cancer cell lines.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sesquiterpenos
/
Abelmoschus
Limite:
Humans
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2019
Tipo de documento:
Article