DHA and ARA addition to infant formula: Current status and future research directions.
Prostaglandins Leukot Essent Fatty Acids
; 128: 26-40, 2018 01.
Article
em En
| MEDLINE
| ID: mdl-29413359
ABSTRACT
Docosahexaenoic acid (DHA) and arachidonic acid (ARA) are present in breast milk and play important roles in early infant development. A supply of these fatty acids in infant formula (typically following breast milk as a model with ARA > DHA) is thought to be important since endogenous synthesis is insufficient to maintain tissue levels equivalent to breast-fed infants. Intervention studies assessing the impact of DHA- and ARA-supplemented formulas have resulted in numerous positive developmental outcomes (closer to breast-fed infants) including measures of specific cognition functions, visual acuity, and immune responses. A critical analysis of outcome assessment tools reveals the essentiality of selecting appropriate, focused techniques in order to provide accurate evaluation of DHA- and ARA-supplemented formulas. Future research directions should encompass in-depth assessment of specific cognitive outcomes, immune function, and disease incidence, as well as sources of experimental variability such as the status of fatty acid desaturase polymorphisms.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácidos Docosa-Hexaenoicos
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Ácido Araquidônico
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Fórmulas Infantis
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Fenômenos Fisiológicos da Nutrição do Lactente
Limite:
Humans
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Infant
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Newborn
Idioma:
En
Revista:
Prostaglandins Leukot Essent Fatty Acids
Ano de publicação:
2018
Tipo de documento:
Article