Neonatal Cytomegalovirus Palatal Ulceration and Bocavirus Pneumonitis Associated With a Defect of Lymphocyte Cytotoxicity Caused by Mutations in UNC13D.
J Pediatric Infect Dis Soc
; 8(1): 73-76, 2019 Mar 28.
Article
em En
| MEDLINE
| ID: mdl-29415165
ABSTRACT
Single gene defects that impair lymphocyte cytotoxicity can predispose to severe viral infection that normally remains subclinical. The classic severe presentation is hemophagocytic lymphohistiocytosis. Here, we report the case of a neonate who presented with cytomegalovirus palatal ulceration and bocavirus pneumonitis secondary to impaired cytotoxicity caused by biallelic mutations in the UNC13D gene.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Viral
/
Úlcera
/
Linfócitos
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Infecções por Citomegalovirus
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Infecções por Parvoviridae
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Palato Duro
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Citotoxicidade Imunológica
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Bocavirus Humano
/
Proteínas de Membrana
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
/
Male
/
Newborn
Idioma:
En
Revista:
J Pediatric Infect Dis Soc
Ano de publicação:
2019
Tipo de documento:
Article