[PREDICTORS OF UNFAVORABLE OUTCOME IN PATIENTS WITH ABDOMINAL SEPSIS.]
Anesteziol Reanimatol
; 61: 209-215, 2017 Sep.
Article
em Ru
| MEDLINE
| ID: mdl-29465206
ABSTRACT
OBJECTIVE:
The study focuses on identifying predictors of treatment outcome in abdominal sepsis (AS) in humans. SUBJECTS ANDMETHODS:
70 patients underwent determination of blood pressure, heart rate, SpO , the content of leu- kocytes, albumin, C-reactive protein, fibrinogen and TNF-a in arterial (femoral artery) and venous (subclavian vein) blood. Automatic biochemical analyzer Cobas-Integra 400 ('Roche", Switzerland), the test system Microlab STAR ELISA kit reagents "alpha TNF - ELISA - best" were used during the research. System statistical analysis included paired comparison of patients with favorable (n=27) and lethal (n=43) outcome, correlation, cluster; discriminating analysis, multidimensional scaling and plotting ROC curves with sensitivity and specificity indicators predictive value.RESULTS:
Identfied predictors of outcome inpatients,from which to form a predictive model of CRP fibrinogen, albumin, and TNF-a arterial blood. It is established that if the basic treatment of the patient CRP <9,8 g/l,fibrinogen >3,43 g/l, albumin <28,9 gl and TNF-a <499,3 ng/ml, the probability of death was statistically significantly higher thanfavorable.CONCLUSION:
It is assumed that therapeutic measures should be aimed at correction of the above mentioned indicators.
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Coleções:
01-internacional
Contexto em Saúde:
4_TD
Base de dados:
MEDLINE
Assunto principal:
Sepse
/
Mediadores da Inflamação
/
Infecções Intra-Abdominais
/
Modelos Biológicos
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Anesteziol Reanimatol
Ano de publicação:
2017
Tipo de documento:
Article